There have been several updates and developments pertaining to Parkinson’s disease treatment in recent times. A global scientific team has come out with a revelation on causes for specific genetic types of Parkinson’s disease with mutated PARK7 and has zeroed in on prospective pharmacological treatments for the same. The study on this was released in Science Translational Medicine and was spearheaded by Professor Rejko Kruger from the noted Luxembourg Centre for Systems Biomedicine or LCSB, University of Luxembourg. Experiments were carried out on cell cultures (patient-based) in laboratories for unearthing possible future treatments for Parkinson’s disease. This is one of the latest and most revolutionary updates worldwide.
Research has already revealed earlier that the DJ-1 protein has a vital role to play in ensuring the smooth functioning of nerve cells. Various nerve cells die out in case insufficient amounts of DJ-1 are produced by our bodies, leading to Parkinson’s disease and similar neuro-degenerative issues. The scientific team has been successful in identifying a vital error in the process of such production which is called as splicing and plays a role in development of Parkinson’s. Owing to this defect, the protein development is hampered and the findings throw up a new point of treatment for protein synthesis malfunction with the right medicines.
More insights on Parkinson’s treatment updates
A physiotherapist has long been recommended by medical practitioners for the treatment procedure of Parkinson’s in conjunction with other medical treatments. The report released in the journal fundamentally brings about a sea change in how the disease causes are perceived while opening up new treatment opportunities now. Owing to skill cells being donated through biopsies, these cells were programmed by scientists to grow in vitro into nerve cells. Clinical trials will now be undertaken for the substances before they are officially used for treatments. University of Bath scientists had found various protein based structures that were considerably relevant for the onset of Parkinson’s earlier.
This disease affects the nervous system, hindering movement (which is why physiotherapy is beneficial) and symptoms start from tremors in the hands and other little fluctuations, going up to talking and walking difficulties with the progress of the disease. As per estimates, a whopping 10 million people worldwide are impacted by Parkinson’s disease which is the second commonest neurodegenerative ailment after Alzheimer’s. The ailment takes place owing to nerve cell losses in a brain component known as substantia Nigra. Nerve cells here hold responsibility for producing the dopamine chemical. These two studies comprise some of the latest updates on treatment of Parkinson’s disease and should pave the way for more breakthroughs in the future as well. They may spawn specific medicines and other treatment forms that may help in relieving symptoms faster while attacking the disease from a wholly different point of view.
Physiotherapy is highly recommended for coping with mobility issues in case of the onset of Parkinson’s disease. A trained and certified physiotherapist will be able to help with movement problems while relieving pain and discomfort greatly at the same time.
Reference Links:
https://www.drugtargetreview.com/news/71364/stem-cells-used-to-identify-potential-treatments-for-parkinsons-disease/
Parkinson’s Disease Treatment May Be Unlocked by Protein Structures
